The Utopia Dimension was a universe discovered by Lady Aesculapius and Jason Jackson during their travels through the multiverse. Its inhabitants had developed a device capable of destroying other universes in an instant.
Shortly after this discovery, while Aesculapius's Factory of Crystal was floating through the remains of a "recently-destroyed universe", Meistras killed Aesculapius's current incarnation using a booby-trapped parcel as a twisted "warning" to her next self to stay away from the secrets of the Utopia Dimension, stating that it could mean her permanent death, even as a Firmament. Naturally, this only spurred her and Jason to decide to investigate further, thinking there must be more to this, when they'd previously assumed that the existence of such a universe was just a "random act of probability" with no further significance beyond the tragedy of the circumstances. (PROSE: Life After Death)