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Peri Brown has been dropped off in New York City to see the Dodgers play baseball. The Sixth Doctor and Frobisher are travelling in the TARDIS to pick her up when they are hit by a time cannon — technology only Gallifrey is supposed to have. To find and destroy it, the Doctor materialises the TARDIS near the cannon on the planet Hedron. The Hedrons have used the cannon to destroy all traces of genetic imperfection in their species.
As the Doctor and Frobisher exit the TARDIS, they are captured by a robot, placed with the other genetic imperfections and hit with the time cannon. This sends them to prehistoric Earth. The TARDIS is also hit by the cannon and goes with them. The Doctor locates the cube of genetic imperfections and takes it to prevent it from contaminating life on Earth. However, before Frobisher and he can reenter the TARDIS, bodies of dead Hedrons begin to appear. It seems the Hedrons are continuing to use their cannon.
Although he is desperate to prevent the Hedrons from contaminating Earth any further, the Doctor decides that he should pick up Peri in case she can help talk to the Hedrons. Materialising in New York City in the year 1986, the Doctor and Frobisher find Earth controlled by sentient reptiles. Apparently the Hedrons' genetic material has altered the course of life on Earth so that humans never evolved.
The Doctor and Frobisher make a hasty retreat and return to prehistoric Earth to attempt to reverse the damage done by the Hedrons. While the Doctor mulls over the situation, Frobisher decides to grab a bite to eat, but before long a large aquatic dinosaur decides to eat him. Trying to rescue Frobisher, the Doctor grabs the nearest object and hurls it at the dinosaur. However, the nearest object is a sphere containing Hedron genetic material. It smashes open, causing the dinosaur to flee but also irreversibly contaminating prehistoric Earth.
Angry that Frobisher has caused him to further contaminate life on Earth, the Doctor and Frobisher return to Hedron so they can at least destroy the time cannon and prevent it from doing any further damage to the universe. When they arrive on Hedron, however, they find that everyone has died through some terrible cataclysm. They find a recording from one of the last Hedrons and learn that the cause of the destruction was a spaceship that had crashed on the planet, releasing microbes and poisons which the Hedrons had eliminated and to which their immune systems had no defence. As it turns out, the origin of the deadly space ship was none other than the planet Earth. Thus, time had healed its own wounds and the genetic material that the Hedrons had banished from their planet had come back to them with deadly results.
The Doctor destroys the time cannon and Frobisher and he take the TARDIS back to Peri's baseball game. As the Doctor exits the TARDIS he wonders if they will be able to sneak into the game without paying. This seems unlikely, however, as the TARDIS has materialised in the middle of the baseball field, much to the players' confusion.
- Frobisher takes on the form of Godzilla to scare away two of the reptiles that attack him and the Doctor. He then says afterwards that he got the idea from a video he had watched with Peri.
- Ruminating on the infection spreading through the prehistoric Earth, the Doctor reflects that: "[He's] a Doctor, not an undertaker."
- According to the Doctor, the mechanics of a temporal disruption pulser (or time cannon) are meant to be a closely guarded Gallifreyan secret.
- Although Peri is mentioned several times, she does not actually appear in this story. Only as a cameo on the second-last panel, looking on as the TARDIS materialises at the centre of the baseball match.
- This story was reprinted in The World Shapers graphic novel.
- The baseball scene in "Part One" contains several minor details which were pointed out to be incorrect in a letter printed in the letters column of DWM 117. The comic called the Dodgers' home stadium "Dodgers Stadium", when the stadium's correct name was "Ebbets Field". Also, there was never an opposing baseball team called the "Redskins" (though there is an American football team by that name and baseball team called the "Reds"). The editorial staff acknowledged these points as errors and responded with an apology.
- The Doctor has temporarily left Peri in New York City before. (COMIC: Kane's Story)
- Frobisher is visibly disturbed by the Hedron massacre, a stark contrast to his earlier, more superficial attitude to the slaughter of Kaon's warriors on Actinon. (COMIC: War-Game)
- The Hedron "genetic waste" expunged from their species contributes to the development of the human species. (TV: City of Death, AUDIO: Bloodtide)
- The alternate timeline in which humanity's ancestors never evolved is populated by a feudal reptillian species. (TV: Doctor Who and the Silurians)
- Facing a total systems failure, the TARDIS is suspended in an interzone. A limbo state that leaves the vessel invisible and its occupants as transparent ghosts. A similar fault befell the TARDIS in TV: The Invasion.