The Keep was a dome-shaped structure located in the Amazon in the 51st century. It was home to the scientist Crivello and his android Marquez. Uber-Marshal Run Run Hsui Leng believed that the Keep contained a great treasure and sought a means to breach the structure. The Eighth Doctor and Izzy Sinclair were brought inside the Keep via transmat by Marquez, who needed the Doctor to communicate with Crivello's Cauldron. After he did so, they evacuated the Keep, which was destroyed when the Cauldron departed for the Crab Nebula. (COMIC: The Keep)
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