In reference to the Fourth Doctor's sense of humour, Romana I told him that sarcasm was "an adjusted stress reaction". (TV: The Ribos Operation)
The Sixth Doctor was noted for his sarcasm, as well, (TV: The Mysterious Planet) as was the Seventh Doctor. (AUDIO: The High Price of Parking) The Eighth Doctor, however, sometimes had trouble recognising it, and seemed unaware of its use on at least one occasion. (PROSE: Dead Time)
While Mr Colchester once expressed that sarcasm was the lowest form of wit, Ng held that it was also the most human. (AUDIO: Eye of the Storm)
When Lucie Miller said "no kidding", she and the Eighth Doctor were not meant to get out, the Doctor asked her why she always resorted to sarcasm. Lucie referred to it as her super power. "I am Sarcasmo, woman of sarcasm. My enemies are struck down by my barbs of steel. [...] Barbs. Barbed comments?" (AUDIO: Human Resources)
The Eleventh Doctor and his Ganger agreed that Amy Pond was very good at sarcasm. She had said, "I'm glad you solved the problem of confusing." (TV: The Almost People)
Sarah Jane Smith told the Fourth Doctor she hated sarcasm, "especially when I'm dying". (TV: The Android Invasion)
The Fifth Doctor noted that Peri Brown, however, was not adept at sarcasm, in response to her attempt at it. "Maybe someone wanted some sand to make some glass so they could blow a new vacuum tube for their reticular vector gauge." (TV: The Caves of Androzani) The Third Doctor noted that sarcasm was always a weak point with the Time Lord messenger who informed him about the Master. (TV: Terror of the Autons)
The First Doctor detected "a hint of sarcasm" in Ian Chesterton, after he said, "Oh, wonderful. I've always wanted one," in response to a scientific explanation given by the Doctor which he did not understand. (TV: "The Executioners")
The Sixth Doctor's "crude sarcasm" was noted by the Inquisitor at his trial: "I'm not so egotistic as to believe all knowledge is at my fingertips." (TV: The Mysterious Planet)
When Steven Taylor volunteered himself to exit the TARDIS, and find out where they were, the First Doctor refused. He didn't think Steven's "present humour" was "fitting" for the occasion, and the soldiers outside wouldn't appreciate his kind of sarcasm. The Doctor himself checked out their whereabouts; the TARDIS was in Troy, during the Trojan War. (TV: The Myth Makers)
The Seventh Doctor noted that, due to their smell-based communication system, the Vrill were incapable of sarcasm, jokes or lying. (AUDIO: Survival of the Fittest)
Jack Harkness told Gwen Cooper and Ianto Jones that "I do the sarcasm around here". Gwen had joked that Jack avoided old people's homes because they'd guess his age and drag him in, to which Ianto responded: "He doesn't want to run into yet another old flame." (AUDIO: The Devil and Miss Carew)
To Jack Harkness introducing himself as such—"note the stripes"—his former fellow Time Agent introduced himself as John—"note the sarcasm". (TV: Kiss Kiss, Bang Bang)
Charley Pollard noted that being the "font of all human knowledge" was better than being the personification of sarcasm and bitterness. (AUDIO: Embrace the Darkness)
A Mark VI combat mechanical detected sarcasm in Graham O'Brien's voice. (PROSE: The Secret in Vault 13)