In the early 21st century, the museum hosted a large number of works of art, including an exhibit completely devoted to Vincent van Gogh. (TV: Vincent and the Doctor) This exhibit ran between 17 March and 29 August 2010. Craig Owens had a poster for the van Gogh exhibit on his fridge. (TV: The Lodger)
During that time, the Eleventh Doctor and Amy Pond visited the museum's van Gogh exhibit. In van Gogh's painting The Church at Auvers, they noticed a face at one of the windows. This prompted them to go back in time to see Vincent.
After a few days, the Doctor and Amy returned with Vincent in tow. They returned to the exhibit and the Doctor questioned Dr Henry Black as to his thoughts on Vincent van Gogh. Telling them that he thought of van Gogh as the greatest artist of all time, Black pushed Vincent to tears.
After taking Vincent back to his own time, the Doctor and Amy returned once more to see if anything had changed. Only two things had; there was no more creature at the window of the church, and his Vase with Twelve Sunflowers was dedicated to Amy. (TV: Vincent and the Doctor)
In the year 3110, the museum was run by a Silurian. The Doctor saved the museum from a giant amoeba that liked the taste of paint, and in return was allowed to select one painting to keep. He chose his favourite painting, The Pandorica Opens, by Vincent van Gogh. The museum had called it, Blue Box Exploding. (PROSE: The War of Art)