Austen usually lived a quiet life in Hampshire, her native country. During her life, she would publish six novels; the first two of them, Sense and Sensibility and Pride and Prejudice, had already been printed before her first meeting with the Doctor, albeit anonimously.
In February 1814, as she was visiting her publisher in London, Miss Austen met the First Doctor, Steven Taylor and Vicki Pallister during the Frost Fair, at the tent where a sea captain showed his collection of objects from his travels, including the Phoenix's egg. Austen assisted Vicki when she fainted, because of the bird lurking at her from the egg; when she introduced herself, the Doctor showed great pleasure to meet her, and declared his admiration for all of her novels, to her greatest surpise. After witnessing the disappearance of the Phoenix's egg and the murder of its owner, she hosted the travellers at her brother's house (where she was staying) and accompanied them to Sir Joseph Mallard's (Deputy Warden of the Royal Mint) party, where she danced a gavotte with the Doctor and was a witness to the disappearance of Lady Georgiana, Sir Joseph's wife. While the Doctor and Steven went looking for Ippolito Valzacchi (an Italian charlatan Vicki saw talk to Georgiana before), she and Vicki traced the egg at St. Cuthbert, a nearby church, with the help of a chimney boy, Jim. Valzacchi tried to hold them hostage for the egg, but the tempestive arrival of the Doctor and Steven, fetched by Jim, prevented that. Miss Austen later contributed to the definitive defeat of the Phoenix, by taking Jim's crowbar and jamming it into the wheel of the Royal Mint's furnace, whose heat the Phoenix was using to hatch the egg and be born. When they parted, she offered the three travellers her hospitality should they ever pass through Hampshire. (AUDIO: Frostfire)
The Sixth Doctor mentioned once having danced a cotillion with Austen, who he said was a "nifty mover". (AUDIO: The Behemoth) The Eleventh Doctor said Austen was "not much of a kisser" (COMIC: Convention Special) while Clara Oswald later described Austen as a "phenomenal kisser". (TV: The Magician's Apprentice) Clara also said that she and Jane played pranks on one another. (TV: Face the Raven)
She was 41 when she died. Jane was resurrected in the City of the Saved, where she appeared as roughly 35 years old and lived in the Sullipsar District. During the Civil War, Jane encouraged her husband Rex Halidom to accept Mayor Ignotus' military summons; when Una duplicated Rex during the mission, he worried that Jane would never learn to accept the fact that there were now two of him. (PROSE: A Hundred Words from a Civil War)
Clara was interrupted by the Twelfth Doctor during a lesson about Pride and Prejudice when he corrected her about the date of writing of the novel. She tried to guess about a rendezvous between the Doctor and the author, but the former countered he knew that as he had read her biography in a copy of the book. (TV: The Caretaker)
When Clara taught Pride and Predjudice to her class, she wrote a quote out from it on her classroom's whiteboard: "It is a truth universally acknowledged, that a single man in possession of a good fortune, must be in want of a wife." (TV: The Caretaker) Upon meeting Mary Shelley, the author of Frankenstein, Graham O'Brien began quoting the same excerpt, saying "It is a truth universally acknowledged...", but the Thirteenth Doctor stopped him before he got any further, saying that he had the wrong writer. (TV: The Haunting of Villa Diodati)
In a timeline where River Song caused time to collapse when she refused to kill the Eleventh Doctor, (TV: The Wedding of River Song) Austen teased of a massacre in her book, Emmerdale, on social media. (PROSE: Just a Minute...)