The Golden Gate Bridge was a San Francisco landmark.
On 14 February 1968, it was reported by the San Francisco Chronicle that a circular symbol with an "R" in it — the symbol of the Revolution Man — appeared on both towers of the bridge. (PROSE: Revolution Man)
In the 25th century of an alternate timeline within the Federation universe, shown to Jean-Luc Picard by the Eleventh Doctor, the Cybermen marched across the Golden Gate Bridge as they invaded San Francisco and Starfleet Academy. (COMIC: Assimilation²)