Doctor Who and the Fangs of Time was a piece of meta-fiction printed within Doctor Who Magazine, showing the writer of the story discussing his childhood growing up with the show with the Doctor himself. Unlike COMIC: TV Action! or COMIC: The Girl Who Loved Doctor Who, there is nothing in the story to suggest that this is set an an alternate dimension where the Doctor's life is chronicled in a TV show, and in fact Sean himself doesn't believe the events of the story to be real within the narrative itself.
The story serves as a transition between the two comics which fell directly before and after its printing — Ground Zero (the final continuous Seventh Doctor story) and Endgame (the first continuous Eighth Doctor story). The Eighth Doctor's run on Doctor Who Magazine would be approached with a more direct and consistent manner, as they decided to form their own story-lines and their own take on the character. This was immediately marked with the introduction of Izzy Sinclair, making the story the first to have an entirely unique set of companions since the early strips featuring Frobisher.
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- Wirrn are seen on a television screen.
- A Sontaran appears in a field.
- Sean constructs a plasticine Kraal.
- The Doctor pulls out a bag of jelly babies.
- A Cyberman rises from a grave.
- An Auton baby is baptised.
- During one of the monologues, images of a Drashig, a Sea Devil, a Silurian, an Axon and a Draconian appear.
- Sean says he used to buy Dalek Deathray lollies.
- This comic is a meta-fictional effort, featuring a "real world" character watching Doctor Who and the Doctor (Fourth) turning up, seemingly the narrator's friend.
- This is the first time the theme tune has been rendered in a comic, with lyrics: