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Chameleon may refer to:
- The Chameleons, a humanoid species. (TV: The Faceless Ones)
- Chameleon Tours, a tourist service the Chameleons ran. (TV: The Faceless Ones)
- Chameleons, a species of Earth-native reptiles. (TV: The Ark)
- Chameleon Arch, a Time Lord device used to alter DNA. (TV: Human Nature)
- Chameleon circuit, a TARDIS component for metamorphosis. (TV: Logopolis)
- Chameleon device, a method of disguise. (COMIC: Samurai's Secret)
- Chameleon Circuit (band), a British YouTube band who write and perform songs about Doctor Who.
- Kamelion, a short-term companion of the Fifth Doctor.