16th century individuals

• Abbot of Amboise
• Albert (The Price of Conviction)
• Ned Alleyn
• Alys
• Anne of Cleves
• Mark Anthony
• Aoi
• Esteban Aribi
• John Arundell
• Arundel (Lost in Time)
• 
  Ashildr
• 
  Autloc
• 
  Aztec captain

• 
  Francis Bacon
• 
  Dolly Bailey
• Robert Bellarmine
• 
  Bentham
• Bernardo (The Doomsday Quatrain)
• Bianca
• 
  Bloodtide
• Anne Boleyn
• Bondot
• Ned Bones
• Hieronymus Bosch
• 
  Tycho Brahe
• 
  British soldier 2 (The Weeping Angels of Mons)
• Giordano Bruno
• 
  Richard Burbage
• Burghley

• 
  Rosanna Calvierri
• 
  Cameca
• Malcome Canker
• Captain of the guard (The Massacre)
• Guard captain (The Ravelli Conspiracy)
• Caravaggio
• Cardinal of Lorraine
• Carla (The Ravelli Conspiracy)
• 
  Carlo (The Vampires of Venice)
• Catherine of Aragon
• 
  Giuseppe di Cattivo
• William Cecil
• 
  Cessair of Diplos
• Chamberlain (The Plotters)
• Chang (Dragon's Claw)
• Anne Chaplet
• Charles IX
• Chiyono
• Roger Colbert
• Gaspard de Coligny
• Christopher Columbus
• Thomas Cromwell
• George Crow

• D'Arcy
• Eleanor Dare
• Virginia Dare
• John Dee
• 
  Doomfinger
• 
  Francis Drake
• Francis Drake (A Storm of Angels)
• Guildford Dudley
• Duke of Medici
• Duke of Northumberland
• Simon Duval

• Johann Eck
• Edward VI
• 
  Elizabeth I
• 
  Ellen (Lost in Time)
• Eric (The Price of Conviction)

• Jane Grey's father
• Johann Faust
• 
  Guy Fawkes
• Ferdinand (Minions of the Moon)
• Anthony Fettiplace
• Gabby Finch
• Joel Finch
• Firking
• 
  First victim
• Richard Fondling
• 
  Francesco
• Francis I
• Francois de Noailles
• Gerhard Frankel
• Ingram Frizer
• Jack Fuller

• 
  Galileo Galilei
• Garland
• Grand Master
• 
  Robert Greene
• Anne Grey
• 
  Jane Grey
• Katherine Grey
• Guard 1 (The Massacre)
• Guard 2 (The Massacre)
• Guard (The Price of Conviction)
• Guido (The Ghosts of N-Space)
• 
  Guido (The Vampires of Venice)
• Gunther (The Price of Conviction)

• Haldann
• Hamnet
• Anne Harney
• Nicholas Harney
• Robert Harney
• Anne Hathaway
• Robert Hay
• Henri III
• 
  Henry VIII
• Ho Lin Chung
• Hodge
• Katherine Howard

• Elizabeth I (A Storm of Angels)
• Iguano
• Innkeeper (The Price of Conviction)
• 
  Inspector (The Vampires of Venice)
• 
  Isabella (The Vampires of Venice)
• 
  Ixta

• 
  Jailer (The Shakespeare Code)
• 
  James I
• James I's father
• James I's mother
• James V
• Inigo Jones
• Judith (The Kingmaker)
• Julius II

• Kadoguchi-roshi
• Kame
• Karl (The Price of Conviction)
• Edward Kelley
• 
  Will Kempe
• Johannes Kepler's wife
• Heinrich Kepler
• 
  Johannes Kepler
• Susanna Kepler
• Kiiro
• Gufuu Kocho
• Kosen

• Landlord (The Massacre)
• William Leaf
• 
  Leo X
• 
  Leonardo da Vinci
• Gaston de Leran
• William Lethbridge-Stewart
• 
  Lilith
• Hans Lippershey
• Yehuda Loevy
• Martin Luther
• 
  Lynley

• 
  Niccolo Machiavelli
• Magistrate (Loups-Garoux)
• Man 1 (The Massacre)
• Man 2 (The Massacre)
• Managra
• 
  Maria (Child of Time)
• Marjorie (Recorded Time)
• 
  Christopher Marlowe
• Mary I
• 
  Matilda (Lost in Time)
• Catherine de Medici
• 
  Guiliano de Medici
• 
  Michelangelo
• Milo (The Doomsday Quatrain)
• Mona Lisa's model
• Molvan (The Eighth Piece)
• 
  The Moon
• Jane Grey's mother
• Jane Mountville
• Nicholas Muss

• John Naps
• Antonio Nicolotti
• Baldassare Nicolotti
• Tomasso Nicolotti
• Norfolk (God Send Me Well to Keep)
• Madame Nostradamus
• 
  Nostradamus

• Officer (The Massacre)
• Otley

• Luca Pacioli
• Paracelsus
• Catherine Parr
• Paul (The Price of Conviction)
• 
  Perfect Victim
• Philip II
• Phoebe
• Piero (Fallen Angels)
• Pincham
• Robert Poley
• 
  Preacher (The Shakespeare Code)
• Charles Preslin
• Priest (Fallen Angels)
• Priest (The Massacre)
• Psychokinetic

• Raju
• Walter Raleigh
• Te Yene Rana
• Raphael (painter)
• William Redcliffe
• 
  Richard III of England
• 
  Richelieu
• Royal guard (The Marian Conspiracy)
• Rudolf II

• Gaspard de Saux-Tavannes