Blasphemy was the show of contempt or mockery for an exalted ideal.
Achilles called Hector's mockery of the Greek gods blasphemy. (TV: The Myth Makers) He made the same charge against Odysseus for his mocking of the First Doctor, whom he believed to be Zeus. (PROSE: The Myth Makers)
The Daleks created from Game Station participants considered the idea that their human origins made them "half-human" (as Rose Tyler observed) to be blasphemous. The Ninth Doctor was taken aback that they had such a concept. (TV: The Parting of the Ways)