Okay, well, most of us, including me, aren't really fond of the Timeless Child. But I can't deny that it does give way for some really fascinating theories.
So, here's another one. I know it has many faults, but I just like to think about this.
Remember how the Doctor always wanted to be ginger. Well, maybe he/she was ginger earlier. And guess who's the ginger incarnation? AMY POND! Well, i know it doesnt really make sense but think about it a little. The crack opened first on Amy's wall. The timelords wanted to send a message to the Doctor. So, what if Amy WAS THE DOCTOR...maybe thats why it opened in her bedroom. Or maybe young Amy never existed and the Time Lords just altered the Doctor's mind about that to avoid paradox (i know doesnt make sense at all, but thats Doctor Who). Now this could also be a better explanation as to why River was a Time Lord. And well, whenever Time Lords regenerate, their entire genetic code changes... so they are not exactly related (this just became even more weird, i'm sorry) But even the Master was attracted to Missy
Let me know your thoughts about it, I know this does not sound good at all, but thinking about this fascinates me