Madam

Madam or Madame was a form of address for women on Earth.

When Vastra integrated into "polite Victorian society", (COMIC: The Lost Dimension) she took up the title of Madame while living on Paternoster Row. (TV: A Good Man Goes to War)

Within minutes of her regeneration, the Thirteenth Doctor questioned why Yasmin Khan called her "madam", unaccustomed to her new gender. When told it was because she was a woman, the Doctor asked if it suited her. (TV: The Woman Who Fell to Earth)