Pandora's box

Pandora's box was the subject of Amy Pond's favourite story as a child, The Legend of Pandora's Box. She said the box contained "all the worst things in the world". (TV: The Pandorica Opens)

Martha Jones compared the transformation of Richard Lazarus via the hypersonic soundwave manipulator to Pandora's box, to which the Tenth Doctor concurred. (TV: The Lazarus Experiment)