Female lead (A Rose by Any Other Name)

An unnamed female lead played a character on the television show Chums.

She filmed a scene from the show's final episode in 2014, opposite a male actor playing the character of Russ. During filming, Russ's actor suddenly turned into a frog, a side-effect on the fabric of time and space from Rose-the-cat attempting to install a cat flap in the Doctor's TARDIS. (COMIC: A Rose by Any Other Name)

Behind the scenes
As Russ and the actor playing him are clear stand-ins for the Friends character and his actor, this would implicitely make the actress and her unnamed character stand-ins for actress  and her Friends character.