Manus Maleficus

The Manus Maleficus was an extremely powerful artifact shaped like a crimson coloured guantlet that most likely originated from an alternate dimension, most likely the Morass.

The Doctor stated that he had not seen anything like this since the Old Time, as well as stating that it was capable of breaking down dimensional barriers, revive long dead civilizations and save another's life. The Crimson Hand used it as a source of their powers, and used the relic to destroy the Skith Homeworld.

In order for this device to work, it requires five individuals, otherwise interacting with the device could be fatal. (DWM: The Crimson Hand)