Singular they

Singular they was a set of personal pronouns widely used to refer to a single individual. (AUDIO: The Eternal Summer, Mindbomb, Disassembled, My Dinner with Andrew, How to Make a Killing in Time Travel, World of Damnation, Enemy Lines, Celestial Intervention, Havoc, The Power of River Song, ScrapeJane, Serenity, The Famished Lands, Conversion; TV: The Lie of the Land, The Haunting of Villa Diodati) It included the pronouns "they", "them" and "themselves". (AUDIO: Enemy Lines)

Singular they was, in some cases, the only correct set of pronouns to apply to someone, on account of the referent's gender, (AUDIO: Orr, Superiority Complex, Poker Face, The Web of Time, et al.) and in others, an expedient and open-ended alternative to constructions such as "he or she", (AUDIO: Appropriation, Subterfuge) encompassing any number of unknowns, (AUDIO: Enemy Lines) and avoiding presumptions. (AUDIO: Crush)

As gender-neutral pronoun
On consulting its styleguide, the sentient Encyclopaedia Britannica decided that "they"/"them" pronouns were the correct terms to apply to the Doctor, thought of generally, once they had regenerated into a new female form. It had briefly considered changing each "he" to "she" in every entry, to reflect the Doctor's latest identity. Rather than revise all past entries to reflect each of the Doctor's new forms, it chose to employ each incarnation's respective pronouns when referring to them specifically, and continued forward with gender-neutral language in all other cases. The encyclopaedia had already been employing they/them pronouns for the Master during the Twelfth Doctor's time. (PROSE: Citation Needed)

Indeed, those who knew the Doctor well, like Jack Harkness, (AUDIO: Piece of Mind), (AUDIO: He Who Wins) or River Song, would sometimes employ they/them pronouns to refer to the Doctor generally, (AUDIO: The Power of River Song, Concealed Weapon, He Who Wins) or when unsure of incarnation. (AUDIO: Concealed Weapon) Clive Finch, who had studied evidence surrounding the Doctor's many incarnations all his life, used they/them pronouns to refer to his hero. He described always wanting to meet them. (PROSE: Rose)

Similarly, Orr, a psychomorph with no fixed gender, used they/them personal pronouns, (AUDIO: Orr, et al.) as did Mx Neon, a transtemporal museum curator. (AUDIO: The Web of Time)

The Ashtallans, who had never so much as encountered gender, used they/them pronouns to refer to one another. (AUDIO: The Invention of Death)

A pronoun with broad applicability
Though it was frequently the case that singular they was employed to refer to an unidentified person — a specific "someone", like an individual or being who had been seen by the speaker but whose identity remained unknown, (AUDIO: Renaissance; PROSE: Rose) or one whose existence was presupposed only by the fruits of their actions, as with the unknown perpetrator of a crime (AUDIO: Enemy Lines, Subterfuge) — they/them pronouns were also used in cases where other, gendered pronouns for whomever was being referenced were already made clear. (AUDIO: Sync) For instance, those who sought to withhold knowledge of the identity of an unknown intruder employed such language to maintain ambiguity, and as a pretence, to obscure their own involvement, until the truth came out. (AUDIO: The Famished Lands)

They/them pronouns were used by speakers who wished to keep the other's identity a secret (AUDIO: The True Saviour of the Universe) or intentionally vague. (TV: The Haunting of Villa Diodati) Some speakers made pointed implications with singular they, just shy of explicitly stating was being referred to. (AUDIO: Emancipation) In some cases, the person was known to the addressee of the sentence, but not to the speaker. (AUDIO: The Lamentation Cipher) Even when both individuals in a conversation knew well to whom they were referring, as with Narvin privately discussing Darkel, (AUDIO: Mindbomb) singular they could be used to intentionally create ambiguity in their statements. (AUDIO: ScrapeJane, Emancipation)

They/them was also used to make a general or hypothetical statement involving a posited individual, serving as a placeholder. (COMIC: Hidden Human History, AUDIO: The Famished Lands) For example, when Ian Chesterton explained to Sharlan that "love is when you are close to someone", he continued with singular they pronouns: "when you want to spend all your time with them, when you care about them very much." (AUDIO: The Invention of Death)

On Earth
On Earth, singular they was in use, and commonly understood without confusion, at least as far back as the 19th century, both among the English (AUDIO: A Photograph to Remember; TV: The Haunting of Villa Diodati) and, across the Atlantic, among Americans. (AUDIO: The Coney Island Chameleon)

In 1945, when Alicia Dowan challenged Winston Churchill's assumption that an unidentified traitorous double agent must be a "he", Churchill repeated her correction — "he, or she" — before switching to they/them as he continued. (AUDIO: Subterfuge)

In the early 21st century, some of Orr's colleagues at Torchwood Three took time to get used to singular they pronouns, which were new to them. Though they stumbled over Orr's unfamiliar pronouns, they soon got used to this gender-neutral language. (AUDIO: Orr, Superiority Complex) Yvonne Hartman, in part due to her personal relations skills, had no such qualms, and consistently used they/them for Orr before even first meeting them, having read the files. (AUDIO: Poker Face)