Grace Holloway

Dr. Grace Holloway was a San Francisco cardiologist and the first companion of the Eighth Doctor. She was a member of the Board of Trustees of the Institute for Technological Advancement and Research.

Biography
Dr. Holloway was known as "Amazing Grace" by her colleagues at Walker General Hospital, where she worked as an on-call cardiologist. The "on-call" part of the job description was particularly annoying to her live-in boyfriend, Brian.

Meeting the Doctor
On the evening of 30 December 1999, Grace was attending the opera when she was paged. She rushed to the hospital to deal with an unusual cardiac case that had come in — a middle-aged man who had suffered minor bullet wounds and who apparently had a heart defect that caused a very irregular heart beat.

Unknown to Grace, her patient had been x-rayed earlier and appeared to have two hearts. While conducting exploratory surgery with a fibre-optic camera, she could not navigate in the man's circulatory system. She inadvertently caused a fatal injury to him and he died on the operating table. Upset at losing a patient, an event witnessed by the hospital's financial supporters, Grace ordered an autopsy. Due to the incident, complicated by the corpse's subsequent disappearance from the morgue, Holloway resigned the next morning rather than be complicit in a cover-up of the events. Brian also left her, taking all his stuff — along with half the furniture.

While she was leaving the hospital, a strange man followed her, claiming to be the man who had died the night before. At first Grace refused to believe him, but was convinced when he took the remains of her probe from his chest. She learned he had undergone regeneration, which had changed his appearance and personality. He was also suffering from amnesia. Hours later, he suddenly regained his memories of being the Doctor, a Time Lord. He celebrated the return of his memories by kissing Grace.

With his memories restored, the Doctor enlisted Grace to help him defeat his enemy the Master. During this time she exclaimed she'd finally found the right guy, only to discover "he's from another planet!"

Grace was possessed for a short while by the Master, who made her betray the Doctor. She later unwillingly opened the Eye of Harmony inside the TARDIS and was killed, but the TARDIS used the Eye to bring her back to life.

After the Master's defeat, the Doctor invited Grace to travel with him as a companion, but she declined, countering that the Doctor should instead join her. After sharing a romantic kiss with her, the Doctor departed in the TARDIS and each went their separate way. (TV: Doctor Who)

After the Doctor
After the Doctor's departure, Grace began examining the remnants of a substance the Master spat at her during the battle. This led her to working with an MI6-sponsored genetics lab in hopes of creating a human-Time Lord hybrid capable of regeneration. When Holloway was later reunited with the Doctor, he chastised her for this, though they ultimately reconciled and parted company with another kiss. (DWM: The Fallen)

Grace Holloway's ultimate fate is unknown, but the Doctor indicated that he was familiar with her work and that she was destined to do "great things". (TV: Doctor Who) Holloway interpreted this as being a reference to her work with MI6 on the human/Time Lord hybrid. (DWM: The Fallen) Her longterm impact on the Doctor is evident in that some time later, he experienced a hallucination that he and Grace were married. (DWM: The Glorious Dead) She survived the Cyberman invasion of Earth in 2004 and concluded that the Doctor must have stopped them. (DWM: The Flood)

As of 2010, Grace was looking into new breakthroughs in surgery. (PROSE: Death of the Doctor)

Personality
Grace was intelligent, feisty and independent, with a strong sense of humour and a love for opera. She was initially doubtful of the Doctor's claims, both about his identity and his apocalyptic predictions. However, once convinced through evidence, she proved a resourceful ally. Grace soon fell in love with the Doctor noting that "[she] had finally found the right guy and he's from another planet". Despite this, she refused the Doctor's offer to travel with him and to learn about her future, preferring for it to remain unknown. (TV: Doctor Who)

Habits and quirks
Grace expressed an interest in Puccini's operas (playing a recording of Madame Butterfly in the operating theatre while working on the Doctor) and the art of Leonardo da Vinci (the Doctor remarks, on seeing a da Vinci print on the wall of Grace's apartment, "He had a terrible cold when he drew that"). (TV: Doctor Who)

Behind the scenes

 * Grace at one point exclaimed, "I finally found the right guy and he's from another planet!". Although the 1963-89 series occasionally gave subtle hints of attraction and even romance between the Doctor and other characters, this is the first time a character, identified as a companion, had been heard to directly express attraction towards the Doctor on screen.
 * According to media coverage of the film in 1996, had Doctor Who been revived as a series at that time, Grace Holloway would not have continued as a regular companion.
 * However, Philip David Segal, the producer of the TV Movie, stated for the record that Dr. Grace Holloway would have returned as the Eighth Doctor's companion had Fox greenlit the series. Mr. Segal made this statement during the "TV Movie Reunion" Panel Discussion at the Gallifrey One Convention held in Los Angeles on Saturday, February 18, 2012.
 * In the video game Bioshock 2 there is a character also called Grace Holloway.
 * Grace is in rare company as one of the only companions to have been present in every televised story of a given incarnation of the Doctor, to date sharing the distinction only with Rose Tyler (with the Ninth Doctor).