1555

The Sixth Doctor and Evelyn Smythe visited England of January 1555, in pursuit of the source of a temporal nexus that was causing Smythe's family to disappear from the timestream. Posing as Queen Mary's physician, the Doctor discovered that it was Smythe's own actions in encouraging an attempt on Mary's life that was paradoxically causing the nexus. Averting these attempts - after a spell in the Tower of London - the TARDIS leaves England, with Mary praying for the Doctor to return and for the safe birth of an heir, neither of which come to pass. (BFA: The Marian Conspiracy)