First Proliferation

The First Proliferation was an event in the Dark Times of the universe. The Tenth Doctor remembered it as "life's opening lunges from impossible planets circling frozen stars and black suns," before the rise of the Old Ones. (PROSE: The Knight, The Fool and The Dead)

According to the Olympians, the Proliferation was caused when Prometheus stole the life spores and spread them across the rest of the universe, creating the first life forms outside of Olympus. (COMIC: The Life Bringer!)

The Tenth Doctor speculated that the Hond were one of the first species, "the primordial ooze" given sentience, created in constant pain as a result of "the universe not quite knowing what life was like yet." (COMIC: Defender of the Daleks) The Kamishi, also known as the First Race, were another one of the earliest known civilisations. (AUDIO: The Rulers of the Universe) The Grey Man stated that the first humanoids were the first species of humanoids to evolve in the universe. (PROSE: Falls the Shadow)