2066

On 3 March 2066, Captain Karl Taylor was sent to investigate mysterious alien signals from Earth's moon, but the sights and sounds of the alien "city" he encountered were entirely incomprehensible to human perceptions. Taylor ordered his people to open fire, apparently fearing they were under attack. This was the start of a war between the alien Myloki and PRISM, the secret organisation created to fight the invaders. The Myloki attacked by transforming ordinary humans into their puppets. Most were merely drone-like zombies known as Shiners, but two were different. One was Captain Taylor, who was sent back to Earth as a walking, indestructible, reanimated corpse — an emotionless killing machine. The other was Captain Grant Matthews, who was killed and duplicated while on a routine escort mission. His duplicate was caught and deprogrammed of his Myloki conditioning and, like Taylor, was literally indestructible. (PROSE: The Indestructible Man)

On the last day of this year, Captain Jack Harkness visited a bar on Zog during New Year's Eve celebrations. There, an individual of an unnamed species gave him instructions for the either earlier or later version of him. This version, upon opening a box on 7 August 1941, relived these experiences. (COMIC: Overture)

Some time during 2066, the First Doctor, John and Gillian battled the Trods for the first time on their native planet Trodos. (COMIC: The Trodos Tyranny)