Grace O'Brien

Grace O'Brien was the paternal grandmother of Ryan Sinclair. She lived in Sheffield with her second husband, Graham O'Brien, whom she met during her work as a chemo nurse. Grace would often attempt to teach Ryan how to cycle, which he struggled with due to dyspraxia.

Whilst returning home after an unsuccessful session, Grace and Graham were caught when a swarm of gathering coils attacked their train in search of Karl Wright. She, along with Graham, Ryan and Yasmin Khan, helped the Doctor battle both the coil and its controller, Tzim-Sha.

While the Doctor was recovering from her recent regeneration, she slept on the sofa in Grace and Grahams' home, and Grace and Ryan witnessed the residual regeneration energy swirling around the Doctor's body, and Grace felt her wrist and announced she had a double pulse.

Grace was electrocuted whilst trying to disable the coil and fell. Mortally wounded, she died in Graham's arms. (TV: The Woman Who Fell to Earth)