Tobacco

The First Doctor once smoked tobacco from a pipe. (TV: "The Cave of Skulls") Samuel Pike's smuggling ring often imported and exported tobacco. (TV: The Smugglers)

The Fourth Doctor told George Litefoot that there was no tobacco where Leela came from when she did not recognise what a smoking pipe was. Litefoot concluded it sounded healthy but exceedingly dull. (TV: The Talons of Weng-Chiang)

According to Susan Foreman, the Coal Hill Staff Common Room stank of rotten tobacco. (PROSE: Time and Relative)

In the 21st century, cigarette boxes advertised that "SMOKING IS BAD." (TV: Out of Time) In London in 2007, it was illegal to sell tobacco to anyone under 16. (TV: Love & Monsters) By 2016, at least in London, it was illegal to sell tobacco products to those under the age of 18. (TV: For Tonight We Might Die)

Tobacco became rare in the aftermath of the 22nd century Dalek invasion. (PROSE: Legacy of the Daleks)