Human-Time Lord Meta-Crisis

A Human-Time Lord Meta-Crisis is the term applied to a hybridized organism that combines the traits of a Time Lord and Human. Only two have been known to exist- "The DoctorDonna" and the Meta-Crisis Tenth Doctor. The former was reverted to her Human self, as the Human brain cannot hold a Time Lord Consciousness so the original Tenth Doctor had to erase Donna's mind. (DW: Journey's End)