Soroptimists

The Soroptimists were a cabal of women - Iris Wildthyme described them as "a passive-agrressive Mafia- they can force you to do pretty much anything just by making you feel guilty". She also claimed that they were common group of adversaries, but Panda said that Iris had never mentioned them before. (PROSE: Iris Wildthyme and the Unholy Ghost)

Behind the scenes

 * In reality, Soroptimist International seem to be more benign than their N-Space, are an organisation dedicated to gender equality and human rights. Although the N-Space counterpart could still stand for the same things, it doesn't make sense why Iris would be opposed to them.