Orient Express

The Orient Express was, as noted by the Twelfth Doctor, a name given to many trains throughout history. (TV: Mummy on the Orient Express) The original Orient Express was a long-distance passenger train originally operated by the Compagnie Internationale des Wagons-Lits on Earth. One Orient Express was built that travelled in space.

Original Orient Express
The two city names most intimately associated with the Orient Express were Paris and Istanbul, the original endpoints of the service. In 1887, Sherlock Holmes and Dr. Watson were riding on the Express through Austria when they were stopped by the train of Pope Leo XIII, who commissioned Holmes to investigate the disappearance of books from the Library of St John the Beheaded in London. (PROSE: All-Consuming Fire)

The train was perhaps most famous for being the setting of a detective novel, Murder on the Orient Express, written in 1934 by Agatha Christie and featuring her Belgian detective character Hercule Poirot. This was inadvertently inspired by Donna Noble, when she met the writer in 1926. It is unlikely, however, that, per Donna's suggestion, the book was copyrighted "Donna Noble." (TV: The Unicorn and the Wasp)

Orient Express in space
A reproduction of the Orient Express ferried passengers in space. On one occasion it was having trouble with an "Egyptian Goddess" who had escaped from the Seventh Obelisk. (TV: The Big Bang)

This spacefaring Orient Express would later be visited by the Twelfth Doctor and Clara Oswald. The Foretold, a mythical mummy, murdered several passengers. The Doctor explained it to be a soldier, waiting to be dismissed from his duties. When the Time Lord attempted to find out who had organised the gathering on the train, its computer, Gus blew up the vehicle. (TV: Mummy on the Orient Express)