The Sixth Doctor: The Last Adventure

 was a full cast audio anthology released on 17 August 2015 by Big Finish Productions as part of The Sixth Doctor Adventures. It featured Colin Baker as the Sixth Doctor, Miranda Raison as Constance Clarke, India Fisher as Charlotte Pollard, Lisa Greenwood as Flip Jackson, Bonnie Langford as Melanie Bush, Christopher Benjamin as Henry Gordon Jago, Trevor Baxter as George Litefoot and Michael Jayston as The Valeyard.

It was notable for being the first time the events leading up to the Sixth Doctor's regeneration were portrayed in performed media, giving Colin Baker the chance to finally do a regeneration story for his Doctor, 28 years after leaving the show. It was also notable for introducing the companion Constance Clarke and seeing the final chronological encounter between the Sixth Doctor and the Valeyard.

The anthology was comprised of four separate, linked stories interspersed throughout different phases of the Sixth Doctor's lifetime, each seeing him travelling with a particular companion, and working progressively further into his life until reaching his final story. The stories can be viewed as one large arc to see how the pieces of the Valeyard's plot all fit together, or viewed independently at the corresponding points of the Sixth Doctor's life in the timeline of his audios and slowly working up to a grand denouement.

Publisher's summary
A very special story which at last provides a heroic exit for Colin Baker's much-loved Time Lord. Four hour-long episodes, connected by the presence of the Valeyard, the entity that exists between the Doctor's twelfth and final incarnations.