Manus Maleficus

The Manus Maleficus was an extremely powerful artefact shaped like a crimson-coloured gauntlet that probably originated in an alternate dimension, most likely the Morass.

The Tenth Doctor stated that he had not seen anything like this since the Old Times, and that it was capable of breaking down dimensional barriers, reviving long dead civilizations, and saving another's life. The Crimson Hand used it as a source of their powers, and used the relic to destroy the Skith Homeworld.

In order for this device to work, it required five individuals; otherwise interacting with the device could be fatal. (DWM: The Crimson Hand)