Buckingham Palace

Buckingham Palace was the London home and primary residence of the British monarchy.

19th century
In 1889, Li H'sen Chang was scheduled to perform for Queen Victoria at Buckingham Palace but he was killed one month earlier. (TV: The Talons of Weng-Chiang)

21st century
In 2008, during the reign of Elizabeth II, most residents of London left the city out of fear over an alien invasion. Elizabeth II herself chose to stay behind. A starship fashioned to look like the Titanic was about to crash into the palace until the Tenth Doctor, at the controls, managed to avert the disaster. (TV: Voyage of the Damned)

The TARDIS was parked in the grounds of Buckingham Palace prior to the Tenth Doctor being tranported to San Helios. According to the Doctor, the Queen "doesn't mind". (TV: Planet of the Dead)

The palace was destroyed in the 22nd century Dalek invasion. (PROSE: Legacy of the Daleks)

Alternative timelines
In one timeline, Buckingham Palace was the home of Holy Roman Emperor Winston Churchill. He returned to the palace on his mammoth from a conference in Gaul with Cleopatra. (TV: The Wedding of River Song)

Parallel world
In a parallel world, the Titanic did crash into the Palace, causing a nuclear explosion. (TV: Turn Left)

Behind the scenes

 * According to the book Doctor Who: The Writer's Tale, Russell T Davies' original draft of Voyage of the Damned had the Titanic demolish part of the palace, leading the Queen to curse the Doctor (continuing the recurring recent theme of the Doctor making enemies with British royalty), but this was dropped as too negative for a holiday special. His later script, Turn Left, did allow the ship to destroy the palace, and most of southern England, but in an alternate timeline.